The influence of recombination on human genetic diversity

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The Influence of Recombination on Human Genetic Diversity

In humans, the rate of recombination, as measured on the megabase scale, is positively associated with the level of genetic variation, as measured at the genic scale. Despite considerable debate, it is not clear whether these factors are causally linked or, if they are, whether this is driven by the repeated action of adaptive evolution or molecular processes such as double-strand break formati...

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ژورنال

عنوان ژورنال: PLoS Genetics

سال: 2005

ISSN: 1553-7390,1553-7404

DOI: 10.1371/journal.pgen.0020148.eor